CD94 Rekombinanter Antikörper

CD94 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

241704E11

Kat-Nr. : 98172-1-RR

Synonyme

241704E11, Killer cell lectin-like receptor subfamily D member 1, KLRD1, KP43, NK cell receptor

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  FC experiment of human PBMCs using 98172-1-RR

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD94 Rabbit RecAb (98172-1-RR, Clone: 241704E11) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 488 Anti-Human NCAM1/CD56. Cells were not fixed. Lymphocytes were gated.

• 

  FC experiment of human PBMCs using 98172-1-RR

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD94 Rabbit RecAb (98172-1-RR, Clone: 241704E11) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. Lymphocytes were gated.

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  Affinity and Kinetic Characterization of 98172-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98172-1-RR against Human CD94 were performed. The affinity constant is below 3.17 nM.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: humane PBMCs

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

98172-1-RR bindet in FC CD94 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Rekombinantes Protein
• Vollständiger Name: killer cell lectin-like receptor subfamily D, member 1
• Berechnetes Molekulargewicht: 179 aa, 20 kDa
• GenBank-Zugangsnummer: BC028009
• Gene symbol: CD94
• Gene ID (NCBI): 3824
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2 - 8°C. Stable for one year after shipment.

Hintergrundinformationen

CD94, also known as the killer cell lectin-like receptor (KLR) family member, is a type II integral membrane protein related to the C-type lectin superfamily. It is specifically expressed on natural killer (NK) cells and a subset of T cells, and plays a crucial role in stimulating NK cell cytolysis and the release of tumor necrosis factor. CD94 can form heterodimers with different NKG2 proteins (e.g., NKG2A, NKG2C, NKG2E, or NKG2F) to balance the function of NK cells and CD8+ T cells.