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CD98/SLC3A2 Rekombinanter Antikörper

CD98/SLC3A2 Rekombinant Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241755A11

Kat-Nr. : 84387-6-PBS

Synonyme

CD98, SLC3A2, 241755A11, 4F2 cell-surface antigen heavy chain, Amino acid transporter heavy chain SLC3A2

Filter:
  • Western Blot (WB) analysis of various lysates using CD98/SLC3A2 Recombinant antibody (84387-6-RR)

    WB analysis using 84387-6-RR (same clone as 84387-6-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84387-6-RR (CD98 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84387-6-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of HepG2 cells using CD98/SLC3A2 Recombinant antibody (84387-6-RR)

    IF Staining of HepG2 using 84387-6-RR (same clone as 84387-6-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using CD98 antibody (84387-6-RR, Clone: 241755A11 ) at dilution of 1:250 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84387-6-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of A431 cells using CD98/SLC3A2 Recombinant antibody (84387-6-RR)

    IF Staining of A431 using 84387-6-RR (same clone as 84387-6-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed A431 cells using CD98/SLC3A2 antibody (84387-6-RR, Clone: 241755A11 ) at dilution of 1:250 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84387-6-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

84387-6-PBS bindet in WB, IF/ICC, Indirect ELISA CD98/SLC3A2 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen CD98/SLC3A2 fusion protein Eg1948
Vollständiger Name solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
Berechnetes Molekulargewicht68 kDa
Beobachtetes Molekulargewicht68-125 kDa
GenBank-ZugangsnummerNM_002394.5
Gene symbol CD98
Gene ID (NCBI) 6520
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD98 is a 125-kDa type II membrane glycoprotein heterodimer composed of a 40-kDa non-glycosylated light chain (amino-acid transporter) and an 85-kDa glycosylated heavy chain (CD98hc) (PMID: 11507094). CD98hc also interacts with certain integrin b-subunits to regulate cell migration, survival, proliferation, and adhesion/polarity. CD98hc is overexpressed on the cell surface of many cancers and increased CD98hc expression is associated with the development and progression of tumors.(PMID:25084765). Molecular orientation studies have demonstrated that the C-terminal tail of human CD98 (hCD98), which contains a PDZ-binding domain, is extracellular (PMID: 18625289).