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CDC37 Monoklonaler Antikörper

CDC37 Monoklonal Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1C2A6

Kat-Nr. : 66420-1-PBS

Synonyme

CDC37, CDC37A, Hsp90 co chaperone Cdc37, P50CDC37

Filter:
  • Western Blot (WB) analysis of various lysates using CDC37 Monoclonal antibody (66420-1-Ig)

    WB analysis using 66420-1-Ig (same clone as 66420-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 66420-1-Ig (CDC37 Antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66420-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of HeLa cells using CDC37 Monoclonal antibody (66420-1-Ig)

    IF Staining of HeLa using 66420-1-Ig (same clone as 66420-1-PBS)

    Immunofluorescent analysis of (-20℃ Ethanol ) fixed HeLa cells using 66420-1-Ig(CDC37 antibody) at dilution of 1:100 and Alexa Fluor 488-conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66420-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

66420-1-PBS bindet in WB, IF/ICC, Indirect ELISA CDC37 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Maus / IgG2a
Klonalität Monoklonal
Typ Antikörper
Immunogen CDC37 fusion protein Ag0267
Vollständiger Name cell division cycle 37 homolog (S. cerevisiae)
Berechnetes Molekulargewicht 44 kDa
Beobachtetes Molekulargewicht 44 kDa
GenBank-ZugangsnummerBC000083
Gene symbol CDC37
Gene ID (NCBI) 11140
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CDC(cell division control) family of proteins are regulatory proteins involved in the processes of cell cycle and proliferation. CDC37, migrated as a protein of 50 kDa in SDS PAGE, is a co-chaperone protein that recruits several immature client kinases to Hsp90 for proper folding. It functions in association with Hsp90, although little is known of its mechanism of action or where it fits into a folding pathway involving other Hsp90 cochaperones. CDC37 up-regulation is a common early event in some localized human cancers. But, the effect of CDC37 dysregulation in human cells is unclear.