CDK5R1 Monoklonaler Antikörper

CDK5R1 Monoklonal Antikörper für WB, IHC, ELISA

Wirt / Isotyp

Maus / IgG2b

Getestete Reaktivität

Hausschwein, human, Kaninchen, Maus, Ratte

Anwendung

WB, IHC, IF, CoIP, ELISA

Konjugation

Unkonjugiert

Publikationen(6)

CloneNo.

1A3A5

Kat-Nr. : 67503-1-Ig

Synonyme

CDK5 activator 1, CDK5P35, CDK5R, CDK5R1, NCK5A, p23, p25, p35, p35nck5a, TPKII regulatory subunit



Geprüfte Anwendungen

Erfolgreiche Detektion in WBHausschwein-Cerebellum-Gewebe, Maushirngewebe, Maus-Cerebellum-Gewebe, Hausschwein-Hirngewebe, Rattenhirngewebe
Erfolgreiche Detektion in IHCMaushirngewebe, Rattenhirngewebe
Hinweis: Antigendemaskierung mit TE-Puffer pH 9,0 empfohlen. (*) Wahlweise kann die Antigendemaskierung auch mit Citratpuffer pH 6,0 erfolgen.

Empfohlene Verdünnung

AnwendungVerdünnung
Western Blot (WB)WB : 1:5000-1:50000
Immunhistochemie (IHC)IHC : 1:200-1:800
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

67503-1-Ig bindet in WB, IHC, IF, CoIP, ELISA CDK5R1 und zeigt Reaktivität mit Hausschwein, human, Kaninchen, Maus, Ratten

Getestete Reaktivität Hausschwein, human, Kaninchen, Maus, Ratte
In Publikationen genannte Reaktivitäthuman, Maus
Wirt / Isotyp Maus / IgG2b
Klonalität Monoklonal
Typ Antikörper
Immunogen CDK5R1 fusion protein Ag13152
Vollständiger Name cyclin-dependent kinase 5, regulatory subunit 1 (p35)
Berechnetes Molekulargewicht 34 kDa
Beobachtetes Molekulargewicht 34 kDa
GenBank-ZugangsnummerBC020580
Gene symbol CDK5R1
Gene ID (NCBI) 8851
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS with 0.02% sodium azide and 50% glycerol
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Cyclin dependent kinase-5 (Cdk5), is an atypical but essential member of the Cdk family of proline-directed serine/threonine kinases. CDK5R1 encodes p35, a specific activator of the serine/threonine kinase CDK5, which plays a central role in neuronal migration and differentiation during central nervous system development. The p35 form of this protein is proteolytically cleaved by calpain, generating a p25 form.

Protokolle

PRODUKTSPEZIFISCHE PROTOKOLLE
WB protocol for CDK5R1 antibody 67503-1-IgProtokoll herunterladen
IHC protocol for CDK5R1 antibody 67503-1-IgProtokoll herunterladenl
STANDARD-PROTOKOLLE
Klicken Sie hier, um unsere Standardprotokolle anzuzeigen

Publikationen

SpeciesApplicationTitle
humanIF

Nat Commun

GRAMD1B is a regulator of lipid homeostasis, autophagic flux and phosphorylated tau

Authors - Diana Acosta Ingram
humanWB,IF,CoIP

J Pharm Anal

Histone deacetylase inhibitor pracinostat suppresses colorectal cancer by inducing CDK5-Drp1 signaling-mediated peripheral mitofission

Authors - Xiao-Ling Liang
mouseIHC

Mol Ther Nucleic Acids

Implications of miR-148a-3p/p35/PTEN signaling in tau hyperphosphorylation and autoregulatory feedforward of Akt/CREB in Alzheimer's disease.

Authors - Li Zeng
humanWB

Cancer Lett

CDK5RAP3 is a novel super-enhancer-driven gene activated by master TFs and regulates ER-Phagy in neuroblastoma

Authors - Ran Zhuo
WB

Sci China Life Sci

FSD1 inhibits glioblastoma diffuse infiltration through restriction of HDAC6-mediated microtubule deacetylation

Authors - Dake Xiao
humanWB

Acta Pharm Sin B

CDK5-triggered G6PD phosphorylation at threonine 91 facilitating redox homeostasis reveals a vulnerability in breast cancer

Authors - Yuncheng Bei

Rezensionen

The reviews below have been submitted by verified Proteintech customers who received an incentive for providing their feedback.


FH

Jia Kang (Verified Customer) (09-05-2025)

The antibody worked rather well, providing clear images under the microscope. No particular issue with this specific antibody.

  • Applications: Immunofluorescence