CDK5R1 Monoklonaler Antikörper
CDK5R1 Monoklonal Antikörper für WB, IHC, ELISA
Wirt / Isotyp
Maus / IgG2b
Getestete Reaktivität
Hausschwein, human, Kaninchen, Maus, Ratte
Anwendung
WB, IHC, IF, CoIP, ELISA
Konjugation
Unkonjugiert
CloneNo.
1A3A5
Kat-Nr. : 67503-1-Ig
Synonyme
Geprüfte Anwendungen
Erfolgreiche Detektion in WB | Hausschwein-Cerebellum-Gewebe, Maushirngewebe, Maus-Cerebellum-Gewebe, Hausschwein-Hirngewebe, Rattenhirngewebe |
Erfolgreiche Detektion in IHC | Maushirngewebe, Rattenhirngewebe Hinweis: Antigendemaskierung mit TE-Puffer pH 9,0 empfohlen. (*) Wahlweise kann die Antigendemaskierung auch mit Citratpuffer pH 6,0 erfolgen. |
Empfohlene Verdünnung
Anwendung | Verdünnung |
---|---|
Western Blot (WB) | WB : 1:5000-1:50000 |
Immunhistochemie (IHC) | IHC : 1:200-1:800 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, check data in validation data gallery |
Veröffentlichte Anwendungen
WB | See 4 publications below |
IHC | See 1 publications below |
IF | See 2 publications below |
CoIP | See 1 publications below |
Produktinformation
67503-1-Ig bindet in WB, IHC, IF, CoIP, ELISA CDK5R1 und zeigt Reaktivität mit Hausschwein, human, Kaninchen, Maus, Ratten
Getestete Reaktivität | Hausschwein, human, Kaninchen, Maus, Ratte |
In Publikationen genannte Reaktivität | human, Maus |
Wirt / Isotyp | Maus / IgG2b |
Klonalität | Monoklonal |
Typ | Antikörper |
Immunogen | CDK5R1 fusion protein Ag13152 |
Vollständiger Name | cyclin-dependent kinase 5, regulatory subunit 1 (p35) |
Berechnetes Molekulargewicht | 34 kDa |
Beobachtetes Molekulargewicht | 34 kDa |
GenBank-Zugangsnummer | BC020580 |
Gene symbol | CDK5R1 |
Gene ID (NCBI) | 8851 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Protein-A-Reinigung |
Lagerungspuffer | PBS with 0.02% sodium azide and 50% glycerol |
Lagerungsbedingungen | Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
Cyclin dependent kinase-5 (Cdk5), is an atypical but essential member of the Cdk family of proline-directed serine/threonine kinases. CDK5R1 encodes p35, a specific activator of the serine/threonine kinase CDK5, which plays a central role in neuronal migration and differentiation during central nervous system development. The p35 form of this protein is proteolytically cleaved by calpain, generating a p25 form.
Protokolle
PRODUKTSPEZIFISCHE PROTOKOLLE | |
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WB protocol for CDK5R1 antibody 67503-1-Ig | Protokoll herunterladen |
IHC protocol for CDK5R1 antibody 67503-1-Ig | Protokoll herunterladenl |
STANDARD-PROTOKOLLE | |
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Klicken Sie hier, um unsere Standardprotokolle anzuzeigen |
Publikationen
Species | Application | Title |
---|---|---|
Nat Commun GRAMD1B is a regulator of lipid homeostasis, autophagic flux and phosphorylated tau | ||
J Pharm Anal Histone deacetylase inhibitor pracinostat suppresses colorectal cancer by inducing CDK5-Drp1 signaling-mediated peripheral mitofission | ||
Mol Ther Nucleic Acids Implications of miR-148a-3p/p35/PTEN signaling in tau hyperphosphorylation and autoregulatory feedforward of Akt/CREB in Alzheimer's disease. | ||
Cancer Lett CDK5RAP3 is a novel super-enhancer-driven gene activated by master TFs and regulates ER-Phagy in neuroblastoma | ||
Sci China Life Sci FSD1 inhibits glioblastoma diffuse infiltration through restriction of HDAC6-mediated microtubule deacetylation | ||
Acta Pharm Sin B CDK5-triggered G6PD phosphorylation at threonine 91 facilitating redox homeostasis reveals a vulnerability in breast cancer |
Rezensionen
The reviews below have been submitted by verified Proteintech customers who received an incentive for providing their feedback.
FH Jia Kang (Verified Customer) (09-05-2025) | The antibody worked rather well, providing clear images under the microscope. No particular issue with this specific antibody.
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