CDKL5 Polyklonaler Antikörper

CDKL5 Polyklonal Antikörper für WB, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 12973-1-PBS

Synonyme

cyclin dependent kinase like 5, Cyclin-dependent kinase-like 5, EC:2.7.11.22, ISSX, Serine/threonine-protein kinase 9

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  WB analysis using 12973-1-AP (same clone as 12973-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 12973-1-AP (CDKL5 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12973-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 12973-1-AP (same clone as 12973-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 12973-1-AP (CDKL5 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12973-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HepG2 using 12973-1-AP (same clone as 12973-1-PBS)

  HepG2 cells were subjected to SDS PAGE followed by western blot with 12973-1-AP (CDKL5 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12973-1-PBS in a different storage buffer formulation.

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  IP experiment of mouse brain using 12973-1-AP (same clone as 12973-1-PBS)

  IP result of anti-CDKL5 (IP:12973-1-AP, 4ug; Detection:12973-1-AP 1:300) with mouse brain tissue lysate 3200 ug. This data was developed using the same antibody clone with 12973-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

12973-1-PBS bindet in WB, IP, Indirect ELISA CDKL5 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: CDKL5 fusion protein Ag3531
• Vollständiger Name: cyclin-dependent kinase-like 5
• Berechnetes Molekulargewicht: 1030 aa, 114 kDa
• Beobachtetes Molekulargewicht: 100-110 kDa
• GenBank-Zugangsnummer: BC036091
• Gene symbol: CDKL5
• Gene ID (NCBI): 6792
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Cyclin dependent kinase like 5 (CDKL5) may regulate ciliogenesis and neuronal morphogenesis. It has been reported that CDKL5 is associated with epileptic seizures, severe intellectual disability, and autistic features. The CDKL5 protein is a kinase that regulates key phosphorylation events vital to the development of the complex neuronal network of the brain.