• Featured Product
  • KD/KO Validated

CDX2 Monoklonaler Antikörper

CDX2 Monoklonal Antikörper für WB, IF/ICC, ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

Hausschwein, human

Anwendung

WB, IHC, IF/ICC, ELISA

Konjugation

Unkonjugiert

Publikationen(18)

CloneNo.

5A4E6

Kat-Nr. : 60243-1-Ig

Synonyme

5A4E6, Caudal type homeobox 2, Caudal type homeobox protein 2, Caudal-type homeobox protein 2, CDX 3



Geprüfte Anwendungen

Erfolgreiche Detektion in WBCOLO 320-Zellen, HT-29-Zellen, Hausschwein-Kolongewebe, SW 1990-Zellen
Erfolgreiche Detektion in IF/ICCCaco-2-Zellen

Empfohlene Verdünnung

AnwendungVerdünnung
Western Blot (WB)WB : 1:1000-1:6000
Immunfluoreszenz (IF)/ICCIF/ICC : 1:400-1:1600
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

60243-1-Ig bindet in WB, IHC, IF/ICC, ELISA CDX2 und zeigt Reaktivität mit Hausschwein, human

Getestete Reaktivität Hausschwein, human
In Publikationen genannte Reaktivitäthuman
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen CDX2 fusion protein Ag17644
Vollständiger Name caudal type homeobox 2
Berechnetes Molekulargewicht 313 aa, 34 kDa
Beobachtetes Molekulargewicht 33-40 kDa
GenBank-ZugangsnummerBC014461
Gene symbol CDX2
Gene ID (NCBI) 1045
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS with 0.02% sodium azide and 50% glycerol
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CDX2, also named as Homeobox protein CDX-2, is a 313 amino acid protein, which contains one homeobox DNA-binding domain and belongs to the Caudal homeobox family. CDX2 localizes in the nucleus and is involved in the transcriptional regulation of multiple genes expression in the intestinal epithelium. The relative expression of CDX1 to CDX2 protein may be important in the anterior to posterior patterning of the intestinal epithelium and in defining patterns of proliferation and differentiation along the crypt-villus axis. Both Cdx1 and Cdx2 genes must be expressed to reduce tumorigenic potential, to increase sensitivity to apoptosis, and to reduce cell migration, suggesting that the two genes control the normal phenotype by independent pathways.

Protokolle

PRODUKTSPEZIFISCHE PROTOKOLLE
WB protocol for CDX2 antibody 60243-1-IgProtokoll herunterladen
IF protocol for CDX2 antibody 60243-1-IgProtokoll herunterladen
STANDARD-PROTOKOLLE
Klicken Sie hier, um unsere Standardprotokolle anzuzeigen

Publikationen

SpeciesApplicationTitle
humanWB

J Exp Clin Cancer Res

FOLR2+ macrophage depletion from intestinal metaplasia to early gastric cancer: single-cell sequencing insight into gastric cancer progression

Authors - Yuxin He
WB

Aging (Albany NY)

The role of CDX2 in renal tubular lesions during diabetic kidney disease.

Authors - Huiming Liu
  • KD Validated
humanWB,IF

Mediators Inflamm

Vitronectin Destroyed Intestinal Epithelial Cell Differentiation through Activation of PDE4-Mediated Ferroptosis in Inflammatory Bowel Disease

Authors - Wenxu Pan
IF

J Reprod Immunol

Poly(I:C) exposure during in vitro fertilization disrupts first cleavage of mouse embryos and subsequent blastocyst development.

Authors - Zhicheng Wang
humanWB

Chem Biol Interact

6-Formylindolo(3,2-b)carbazole induced aryl hydrocarbon receptor activation prevents intestinal barrier dysfunction through regulation of claudin-2 expression.

Authors - Yuanhang Ma
  • KD Validated
IHC

World J Gastrointest Oncol

Xiaojianzhong decoction prevents gastric precancerous lesions in rats by inhibiting autophagy and glycolysis in gastric mucosal cells

Authors - Jia-Xiang Zhang

Rezensionen

The reviews below have been submitted by verified Proteintech customers who received an incentive for providing their feedback.


FH

A (Verified Customer) (07-15-2025)

Used for caco2 cells and animal colon tissue

  • Applications: Western Blot, Immunohistochemistry
  • Primary Antibody Dilution: 1 to 1000