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CDY1B Polyklonaler Antikörper

CDY1B Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 33231-1-PBS

Synonyme

CDY1, CDY1A, EC:2.3.1.48, Testis-specific chromodomain protein Y 1

Filter:
  • Western Blot (WB) analysis of various lysates using CDY1B Polyclonal antibody (33231-1-AP)

    WB analysis using 33231-1-AP (same clone as 33231-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 33231-1-AP (CDY1B antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 33231-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

33231-1-PBS bindet in WB, Indirect ELISA CDY1B und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen CDY1B fusion protein Ag37962
Vollständiger Name chromodomain protein, Y-linked, 1B
Berechnetes Molekulargewicht540 aa, 60 kDa/554 aa, 62 kDa
Beobachtetes Molekulargewicht65 kDa
GenBank-ZugangsnummerBC132929
Gene symbol CDY1B
Gene ID (NCBI) 253175
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The CDY1B gene, also known as Chromodomain Y-Linked 1B, is a Protein Coding gene located on the Y chromosome. It is one of the two identical copies of the CDY1 gene within the AZFc region of the human Y chromosome. As a histone acetyltransferase, CDY1B exhibits a strong preference for histone 4, suggesting its involvement in both spermatogenic histone replacement and DNA transcription. It plays a significant role in the chromatin remodeling of round spermatid nuclei, contributing to the transition from histone-based chromatin to protamine-based chromatin during spermatogenesis. This transition is essential for the condensation of sperm DNA and the formation of mature sperm. Deletion of either CDY1 can lead to spermatogenic failure and male infertility.