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CEA Monoklonaler Antikörper

CEA Monoklonal Antikörper für ELISA

Wirt / Isotyp

Maus / IgG2b

Getestete Reaktivität

human

Anwendung

ELISA

Konjugation

Unkonjugiert

CloneNo.

3D1A6

Kat-Nr. : 60053-1-Ig

Synonyme

Carcinoembryonic antigen, CD66e, CEA, CEACAM5, Meconium antigen 100

Galerie der Validierungsdaten

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  • Western Blot (WB) analysis of human colon tissue using CEA Monoclonal antibody (60053-1-Ig)

    WB analysis of human colon using 60053-1-Ig

    human colon tissue were subjected to SDS PAGE followed by western blot with 60053-1-Ig (CEA antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

Geprüfte Anwendungen

Empfohlene Verdünnung

AnwendungVerdünnung
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

60053-1-Ig bindet in ELISA CEA und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG2b
Klonalität Monoklonal
Typ Antikörper
Immunogen CEA fusion protein Ag0672
Vollständiger Name carcinoembryonic antigen-related cell adhesion molecule 5
Berechnetes Molekulargewicht 77 kDa
GenBank-ZugangsnummerBC034671
Gene symbol CEACAM5
Gene ID (NCBI) 1048
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Caprylsäure/Ammoniumsulfat-Präzipitation
Lagerungspuffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Carcinoembryonic antigen (CEA), also known as CEACAM5 or CD66e, is a cell surface glycoprotein belonging to the immunoglobulin superfamily, mainly serving as a cell adhesion molecule mediating intercellular contact by both homophilic and heterophilic binding (PMID: 21731662). CEA inhibits anoikis and plays a role in tumorigenesis and metastasis. CEA has been found to be overexpressed in a wide variety of human cancers, including colon, breast, and lung (PMID: 17167768). CEA is a tumor marker and is routinely exploited for diagnosis.