CEACAM1/3/6 (CD66a/c/d) Rekombinanter Antikörper

CEACAM1/3/6 (CD66a/c/d) Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

PE Fluorescent Dye

CloneNo.

240497E12

Kat-Nr. : PE-FcA98061

Synonyme

CEACAM1, CEACAM1/CD66a, 240497E12, BGP, BGP1

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  FC experiment of human peripheral blood leukocytes using PE-FcA98061

  1x10^6 human peripheral blood leukocytes were surface stained with FcZero-rAb™ APC Anti-Human CD16 and 5 ul PE Anti-Human CEACAM1/3/6 (CD66a/c/d) Rabbit RecAb (PE-FcA98061, Clone:240497E12), or 5 ul PE Rabbit IgG Isotype Control RecAb (PE-FcA98136, Clone: 240953C9). Cells were not fixed.

• 

  FC experiment of human peripheral blood leukocytes using PE-FcA98061

  1x10^6 human peripheral blood leukocytes were surface stained with 5 ul PE Anti-Human CEACAM1/3/6 (CD66a/c/d) Rabbit RecAb (PE-FcA98061, Clone:240497E12) or 5 ul PE Rabbit IgG Isotype Control RecAb (PE-FcA98136, Clone: 240953C9). Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: human peripheral blood leukocytes

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Produktinformation

PE-FcA98061 bindet in FC CEACAM1/3/6 (CD66a/c/d) und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CEACAM1/3/6 (CD66a/c/d) fusion protein Eg0314
• Vollständiger Name: carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
• Berechnetes Molekulargewicht: 526 aa, 58 kDa
• GenBank-Zugangsnummer: BC014473
• Gene symbol: CEACAM1
• Gene ID (NCBI): 634
• Konjugation: PE Fluorescent Dye
• Excitation/Emission maxima wavelengths: 496 nm, 565 nm / 578 nm
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide and 0.5% BSA
• Lagerungsbedingungen: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

CEACAM1, also known as CD66a or BGP (biliary glycoprotein), is a member of the cacinoembryonic antigen (CEA) family which belongs to the immunoglobulin superfamily of cell adhesion molecules (PMID: 16919437). CEACAMs play major roles in cell-cell and cell-ECM adhesion and have been implicated in the control of cell proliferation, angiogenesis, and tissue remodeling (PMID: 23021083). CEACAM1 is a transmembrane glycoprotein that is expressed on epithelial, endothelial, and immune cells (PMID: 30314283). CEACAM1 has been demonstrated to play a role in morphogenesis, apoptosis, angiogenesis, cell proliferation, cell motility, fibrosis, and immunity (PMID: 31604530). This antibody is raised against 35-428 aa of human CEACAM1/CD66a and can cross-react with CEACAM6/CD66c and CEACAM3/CD66d.