CEACAM16 Polyklonaler Antikörper
CEACAM16 Polyklonal Antikörper für WB, IHC, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human, Maus, Ratte
Anwendung
WB, IHC, Indirect ELISA
Konjugation
Unkonjugiert
Kat-Nr. : 32196-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
32196-1-PBS bindet in WB, IHC, Indirect ELISA CEACAM16 und zeigt Reaktivität mit human, Maus, Ratten
| Getestete Reaktivität | human, Maus, Ratte |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Polyklonal |
| Typ | Antikörper |
| Immunogen | CEACAM16 fusion protein Ag37542 |
| Vollständiger Name | carcinoembryonic antigen-related cell adhesion molecule 16 |
| Beobachtetes Molekulargewicht | 48 kDa |
| GenBank-Zugangsnummer | BC156855 |
| Gene symbol | CEACAM16 |
| Gene ID (NCBI) | 388551 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Antigen-Affinitätsreinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
CEACAM16 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 16) is a member of the CEA family of cell adhesion molecules. It is a critical component of the tectorial membrane in the inner ear, playing a significant role in maintaining hearing function. Mutations in the CEACAM16 gene are associated with autosomal dominant nonsyndromic hearing loss (DFNA4B), characterized by progressive high-frequency hearing impairment. Research has shown that loss or dysfunction of CEACAM16 leads to structural abnormalities in the tectorial membrane, thereby affecting hearing. The identification of CEACAM16 has provided important insights into the genetic basis of hereditary hearing loss and has implications for the diagnosis and treatment of hearing disorders.





