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CEACAM6/CD66c Rekombinanter Antikörper

CEACAM6/CD66c Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

230475D5

Kat-Nr. : 83203-5-PBS

Synonyme

CEACAM6, 230475D5, Carcinoembryonic antigen-related cell adhesion molecule 6, CD66c, CEAL

Filter:
  • Western Blot (WB) analysis of various lysates using CEACAM6/CD66c Recombinant antibody (83203-5-RR)

    WB analysis using 83203-5-RR (same clone as 83203-5-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 83203-5-RR (CEACAM6 antibody) at dilution of 1:7000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83203-5-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83203-5-RR

    Affinity and Kinetic Characterization of 83203-5-RR

    Biolayer interferometry (BLl) kinetic assays of 83203-5-RR against Human CEACAM6 were performed. The affinity constant is 0.113 nM.

Geprüfte Anwendungen

Produktinformation

83203-5-PBS bindet in WB, Indirect ELISA CEACAM6/CD66c und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen CEACAM6/CD66c fusion protein Eg0056
Vollständiger Name carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
Berechnetes Molekulargewicht 37 kDa
Beobachtetes Molekulargewicht40-100 kDa
GenBank-ZugangsnummerBC005008
Gene symbol CEACAM6
Gene ID (NCBI) 4680
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CEACAM6, also known as CD66c, is a glycosylphosphatidylinositol (GPI)-linked cell surface protein that belongs to the CEACAM family of the immunoglobulin superfamily (PMID: 23903773). It is normally expressed on the surface of myeloid and epithelial surfaces and upregulated preferentially at the apical/luminal membranes of many tumors (PMID: 27595061; 35082925). CEACAM6 plays an important role in cell adhesion, proliferation, tumorigenesis, metastasis, and immunity (PMID: 31797958).