CEACAM6/CD66c Rekombinanter Antikörper

CEACAM6/CD66c Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

241997G1

Kat-Nr. : 98329-3-PBS

Synonyme

CEACAM6, NCA, CEAL, CD66c, Carcinoembryonic antigen-related cell adhesion molecule 6

---

• 

  FC experiment of human peripheral blood leukocytes using 98329-3-RR (same clone as 98329-3-PBS)

  1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human CEACAM6/CD66c Rabbit RecAb (98329-3-RR, Clone: 241997G1) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-conjugated Goat Anti-Rabbit IgG. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98329-3-PBS in a different storage buffer formulation.

• 

  FC experiment of human peripheral blood leukocytes using 98329-3-RR (same clone as 98329-3-PBS)

  1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human CEACAM6/CD66c Rabbit RecAb (98329-3-RR, Clone:241997G1) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-conjugated Goat Anti-Rabbit IgG. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98329-3-PBS in a different storage buffer formulation.

---

Geprüfte Anwendungen

Produktinformation

98329-3-PBS bindet in FC CEACAM6/CD66c und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Rekombinantes Protein
• Vollständiger Name: carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
• Berechnetes Molekulargewicht: 37 kDa
• GenBank-Zugangsnummer: BC005008
• Gene symbol: CEACAM6
• Gene ID (NCBI): 4680
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) belong to the immunoglobulin superfamily of cell adhesion molecules. CEACAMs play major roles in cell-cell and cell-ECM adhesion and have been implicated in controlling cell proliferation, angiogenesis, and tissue remodeling (PMID: 23021083). CEACAM6, also known as CD66c, is a glycosylphosphatidylinositol (GPI)-linked cell surface protein that belongs to the CEACAM family of the immunoglobulin superfamily (PMID: 23903773). It is normally expressed on the surface of myeloid and epithelial surfaces and upregulated preferentially at the apical/luminal membranes of many tumors (PMID: 27595061; 35082925). CEACAM6 plays an important role in cell adhesion, proliferation, tumorigenesis, metastasis, and immunity (PMID: 31797958).