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CETP Polyklonaler Antikörper

CETP Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 30136-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using CETP Polyclonal antibody (30136-1-AP)

    WB analysis using 30136-1-AP (same clone as 30136-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30136-1-AP (CETP antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30136-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

30136-1-PBS bindet in WB, Indirect ELISA CETP und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen CETP fusion protein Ag32722
Vollständiger Name cholesteryl ester transfer protein, plasma
Berechnetes Molekulargewicht 493 aa, 55 kDa
Beobachtetes Molekulargewicht55 kDa,70 kDa
GenBank-ZugangsnummerBC025739
Gene symbol CETP
Gene ID (NCBI) 1071
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Cholesteryl ester transfer protein (CETP) is a plasma glycoprotein which transfers cholesteryl esters, triglycerides, and phospholipids between lipoproteins. In plasma, CETP is mainly associated with HDL particles and catalyzes the transfer of cholesteryl esters from HDL to apolipoprotein (apo) B-containing plasma lipoproteins. Low plasma concentrations of high-density lipoprotein-cholesterol (HDL-C) have long been recognized as a major, independent cardiovascular disease (CVD) risk factor. It demonstrated that altered level of plasma CETP was associated with the increased risk of CVD (PMID: 17991755, PMID: 23477743). CETP can be detected a 70 kDa isoform by glycosylation (PMID: 3281933,PMID: 22056562). It also can be detected 100 kDa dimer (PMID: 7744792).