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Properdin/PFC Polyklonaler Antikörper

Properdin/PFC Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 17192-1-PBS

Synonyme

CFP, BFD, Complement factor P, complement factor properdin, PFC

Filter:
  • Western Blot (WB) analysis of Jurkat cells using Properdin/PFC Polyclonal antibody (17192-1-AP)

    WB analysis of Jurkat using 17192-1-AP (same clone as 17192-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 17192-1-AP (CFP Antibody) at dilution of 1:300 incubated at 4 degree celsius over night. This data was developed using the same antibody clone with 17192-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human spleen tissue using Properdin/PFC Polyclonal antibody (17192-1-AP)

    IHC staining of human spleen using 17192-1-AP (same clone as 17192-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human spleen tissue slide using 17192-1-AP (CFP Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 17192-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human spleen tissue using Properdin/PFC Polyclonal antibody (17192-1-AP)

    IHC staining of human spleen using 17192-1-AP (same clone as 17192-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human spleen tissue slide using 17192-1-AP (CFP Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 17192-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

17192-1-PBS bindet in WB, IHC, Indirect ELISA Properdin/PFC und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Properdin/PFC fusion protein Ag9798
Vollständiger Name complement factor properdin
Berechnetes Molekulargewicht 469 aa, 51 kDa
Beobachtetes Molekulargewicht 50 kDa
GenBank-ZugangsnummerBC015756
Gene symbol CFP
Gene ID (NCBI) 5199
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CFP, also named as Properdin or PFC, is a 469 amino acid protein, which contains 7 TSP type-1 domains. CFP as secreted protein is a positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Properdin deficiency poses a significant risk for severe meningococcal infections (PMID: 22229731). Properdin may be novel biomarker for future risk of type 2 diabetes (PMID: 22338105).