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Properdin/PFC Monoklonaler Antikörper

Properdin/PFC Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

Hausschwein, human, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1D5A9

Kat-Nr. : 66788-1-PBS

Synonyme

CFP, 1D5A9, BFD, Complement factor P, complement factor properdin

Filter:
  • Western Blot (WB) analysis of Jurkat cells using Properdin/PFC Monoclonal antibody (66788-1-Ig)

    WB analysis of Jurkat using 66788-1-Ig (same clone as 66788-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 66788-1-Ig (CFP antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66788-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of human plasma using Properdin/PFC Monoclonal antibody (66788-1-Ig)

    WB analysis of human plasma using 66788-1-Ig (same clone as 66788-1-PBS)

    human plasma were subjected to SDS PAGE followed by western blot with 66788-1-Ig (CFP antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66788-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

66788-1-PBS bindet in WB, Indirect ELISA Properdin/PFC und zeigt Reaktivität mit Hausschwein, human, Ratten

Getestete Reaktivität Hausschwein, human, Ratte
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen Properdin/PFC fusion protein Ag9798
Vollständiger Name complement factor properdin
Berechnetes Molekulargewicht 469 aa, 51 kDa
Beobachtetes Molekulargewicht 50 kDa, 100 kDa, 150 kDa
GenBank-ZugangsnummerBC015756
Gene symbol CFP
Gene ID (NCBI) 5199
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CFP, also named as Properdin or PFC, is a 469 amino acid protein, which contains 7 TSP type-1 domains. CFP as secreted protein is a positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Properdin deficiency poses a significant risk for severe meningococcal infections (PMID: 22229731). Properdin may be novel biomarker for future risk of type 2 diabetes (PMID: 22338105). In plasma, properdin exists as dimers, trimers or tetramers.