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CFP Rekombinanter Antikörper

CFP Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250654E3

Kat-Nr. : 85999-1-PBS

Synonyme

BFD, Complement factor P, complement factor properdin, PFC

Filter:
  • Western Blot (WB) analysis of human plasma using CFP Recombinant antibody (85999-1-RR)

    WB analysis of human plasma using 85999-1-RR (same clone as 85999-1-PBS)

    human plasma were subjected to SDS PAGE followed by western blot with 85999-1-RR (CFP antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85999-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using CFP Recombinant antibody (85999-1-RR)

    WB analysis using 85999-1-RR (same clone as 85999-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85999-1-RR (CFP antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85999-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 85999-1-RR

    Affinity and Kinetic Characterization of 85999-1-RR

    Biolayer interferometry (BLl) kinetic assays of 85999-1-RR against Human CFP were performed. The affinity constant is 0.98 nM.

Geprüfte Anwendungen

Produktinformation

85999-1-PBS bindet in WB, Indirect ELISA CFP und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen CFP fusion protein Eg2219
Vollständiger Name complement factor properdin
Berechnetes Molekulargewicht 469 aa, 51 kDa
Beobachtetes Molekulargewicht 55 kDa
GenBank-ZugangsnummerBC015756
Gene symbol CFP
Gene ID (NCBI) 5199
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CFP, also named as Properdin or PFC, is a 469 amino acid protein, which contains 7 TSP type-1 domains. CFP as secreted protein is a positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Properdin deficiency poses a significant risk for severe meningococcal infections (PMID: 22229731). Properdin may be novel biomarker for future risk of type 2 diabetes (PMID: 22338105).