CHD1L Polyklonaler Antikörper

CHD1L Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32923-1-PBS

Synonyme

ALC1, Amplified in liver cancer protein 1, Chromodomain-helicase-DNA-binding protein 1-like, EC:3.6.4.-

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  WB analysis using 32923-1-AP (same clone as 32923-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32923-1-AP (CHD1L antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32923-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

32923-1-PBS bindet in WB, Indirect ELISA CHD1L und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: CHD1L fusion protein Ag38526
• Vollständiger Name: chromodomain helicase DNA binding protein 1-like
• Berechnetes Molekulargewicht: 101kDa，897aa
• Beobachtetes Molekulargewicht: 101 kDa
• GenBank-Zugangsnummer: NM_004284.5
• Gene symbol: CHD1L
• Gene ID (NCBI): 9557
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CHD1L (Chromodomain Helicase DNA Binding Protein 1-Like), also known as ALC1 (Amplified in Liver Cancer 1), encodes a multifunctional protein involved in various cellular processes such as chromatin remodeling, cell differentiation, and development. CHD1L acts as an ATP-dependent chromatin remodeling enzyme with an ATPase catalytic domain activated by double-stranded DNA. It interacts with PARP1 (poly-ADP-ribose polymerase 1) to promote chromatin relaxation at DNA damage sites, facilitating DNA repair. Overexpression of CHD1L leads to dysregulation of downstream targets in various cancers.