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CHMP4C Polyklonaler Antikörper

CHMP4C Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 16256-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using CHMP4C Polyclonal antibody (16256-1-AP)

    WB analysis using 16256-1-AP (same clone as 16256-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 16256-1-AP (CHMP4C antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16256-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

16256-1-PBS bindet in WB, Indirect ELISA CHMP4C und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen CHMP4C fusion protein Ag9279
Vollständiger Name chromatin modifying protein 4C
Berechnetes Molekulargewicht 233 aa, 26 kDa
Beobachtetes Molekulargewicht35 kDa
GenBank-ZugangsnummerBC014321
Gene symbol CHMP4C
Gene ID (NCBI) 92421
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CHMP4C (Charged multivesicular body protein 4c), also known as SHAX3. It is expected to be located in the cytoplasm and membrane, which is expressed in heart, spleen and kidney. CHMP4C is one of the charged multivesicular protein (CHMP), and is involved in the composition of the endosomal sorting complex required for transport III (ESCRT-III), facilitating the necessary separation of daughter cells. CHMP4C has been proposed to be involved in the progression of different carcinomas. The molecular weight of CHMP4C is 26 kDa. Phosphorylated at Ser-210 by AURKB during cytokinesis: together with ZFYVE19/ANCHR, phosphorylated CHMP4C retains abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis.