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CHRM3 Polyklonaler Antikörper

CHRM3 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 21978-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using CHRM3 Polyclonal antibody (21978-1-AP)

    WB analysis using 21978-1-AP (same clone as 21978-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 21978-1-AP (CHRM3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21978-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

21978-1-PBS bindet in WB, Indirect ELISA CHRM3 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen CHRM3 fusion protein Ag17791
Vollständiger Name cholinergic receptor, muscarinic 3
Berechnetes Molekulargewicht 590 aa, 66 kDa
Beobachtetes Molekulargewicht60-66 kDa
GenBank-ZugangsnummerBC121026
Gene symbol CHRM3
Gene ID (NCBI) 1131
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CHRM3 (M3 muscarinic acetylcholine receptor) is a major player in many kinds of cancer (PMID: 26175851). The expression of muscarinic receptors, mainly the CHRM3, is amplified in several types of tumors, including colon cancer, prostate cancer, endometrial carcinoma, and gastric cancer. Colon cancer overexpresses CHRM3, and post-M3R signaling promotes cell growth via the activation of the epidermal growth factor receptors/ERK and protein kinase C/p38 mitogen-activated protein kinase (MAPK) signaling pathways (PMID: 37744266).