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CHRNA4 Polyklonaler Antikörper

CHRNA4 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 21939-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using CHRNA4 Polyclonal antibody (21939-1-AP)

    WB analysis using 21939-1-AP (same clone as 21939-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 21939-1-AP (CHRNA4 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21939-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

21939-1-PBS bindet in WB, Indirect ELISA CHRNA4 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen CHRNA4 fusion protein Ag16584
Vollständiger Name cholinergic receptor, nicotinic, alpha 4
Berechnetes Molekulargewicht 627 aa, 70 kDa
Beobachtetes Molekulargewicht69 kDa
GenBank-ZugangsnummerBC096290
Gene symbol CHRNA4
Gene ID (NCBI) 1137
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1.