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CHRND Polyklonaler Antikörper

CHRND Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 17864-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using CHRND Polyclonal antibody (17864-1-AP)

    WB analysis using 17864-1-AP (same clone as 17864-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 17864-1-AP (CHRND antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17864-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

17864-1-PBS bindet in WB, Indirect ELISA CHRND und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen CHRND fusion protein Ag12337
Vollständiger Name cholinergic receptor, nicotinic, delta
Berechnetes Molekulargewicht 517 aa, 59 kDa
GenBank-ZugangsnummerBC093923
Gene symbol CHRND
Gene ID (NCBI) 1144
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in this gene are a cause of multiple pterygium syndrome lethal type (MUPSL), congenital myasthenic syndrome slow-channel type (SCCMS), and congenital myasthenic syndrome fast-channel type (FCCMS).