CIB1 Polyklonaler Antikörper

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• KD/KO Validated

CIB1 Polyklonal Antikörper für WB, IHC, IF/ICC, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, IF/ICC, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 11823-1-PBS

Synonyme

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  WB analysis of human liver using 11823-1-AP (same clone as 11823-1-PBS)

  human liver tissue were subjected to SDS PAGE followed by western blot with 11823-1-AP (CIB1 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11823-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HepG2 using 11823-1-AP (same clone as 11823-1-PBS)

  HepG2 cells were subjected to SDS PAGE followed by western blot with 11823-1-AP (CIB1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11823-1-PBS in a different storage buffer formulation.

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  WB analysis of rat testis using 11823-1-AP (same clone as 11823-1-PBS)

  rat testis tissue were subjected to SDS PAGE followed by western blot with 11823-1-AP (CIB1 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11823-1-PBS in a different storage buffer formulation.

• 

  IP experiment of mouse testis using 11823-1-AP (same clone as 11823-1-PBS)

  IP result of anti-CIB1 (IP:11823-1-AP, 4ug; Detection:11823-1-AP 1:300) with mouse testis tissue lysate 4000ug. This data was developed using the same antibody clone with 11823-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 11823-1-AP (same clone as 11823-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer using 11823-1-AP (CIB1 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 11823-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human testis using 11823-1-AP (same clone as 11823-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human testis using 11823-1-AP (CIB1 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 11823-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human testis using 11823-1-AP (same clone as 11823-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human testis using 11823-1-AP (CIB1 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 11823-1-PBS in a different storage buffer formulation.

• 

  IHC staining of rat testis using 11823-1-AP (same clone as 11823-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat testis using 11823-1-AP (CIB1 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 11823-1-PBS in a different storage buffer formulation.

• 

  IHC staining of rat testis using 11823-1-AP (same clone as 11823-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat testis using 11823-1-AP (CIB1 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 11823-1-PBS in a different storage buffer formulation.

• 

  IF Staining of A549 using 11823-1-AP (same clone as 11823-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed A549 cells using CIB1 antibody (11823-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 11823-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

11823-1-PBS bindet in WB, IHC, IF/ICC, IP, Indirect ELISA CIB1 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: CIB1 fusion protein Ag2391
• Vollständiger Name: calcium and integrin binding 1 (calmyrin)
• Berechnetes Molekulargewicht: 22 kDa
• Beobachtetes Molekulargewicht: 22 kDa
• GenBank-Zugangsnummer: BC000846
• Gene symbol: CIB1
• Gene ID (NCBI): 10519
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CIB1(Calcium and integrin-binding protein 1) is also named as CIB, KIP, PRKDCIP. It is an EF-hand-containing protein that binds multiple effector proteins, including the platelet αIIbβ3 integrin and several serine/threonine kinases and potentially modulates their function. It regulates platelet aggregation in hemostasis through a specific interaction with the alphaIIb cytoplasmic domain of platelet integrin alphaIIbbeta3.