CIB2 Polyklonaler Antikörper

CIB2 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32585-1-PBS

Synonyme

Calcium and integrin-binding family member 2, Kinase-interacting protein 2, KIP 2, KIP2

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  WB analysis using 32585-1-AP (same clone as 32585-1-PBS)

  Mouse heart tissue lysate was subjected to SDS PAGE followed by western blot with 32585-1-AP (CIB2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32585-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

32585-1-PBS bindet in WB, Indirect ELISA CIB2 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: CIB2 fusion protein Ag38508
• Vollständiger Name: calcium and integrin binding family member 2
• Berechnetes Molekulargewicht: 22 kDa，187aa
• Beobachtetes Molekulargewicht: 39 kDa
• GenBank-Zugangsnummer: NM_006383.3
• Gene symbol: CIB2
• Gene ID (NCBI): 10518
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The CIB (calcium and integrin binding) protein family has 4 members (CIB1-CIB4), each composed of 4 EF-hand Ca2+-binding motifs (PMID: 27771768). CIB2 is broadly expressed in a variety of tissues, which plays a role in sensory neurons of the ear and eye involved in the regulation of Ca2+ homeostasis (PMID: 28663585; 29084757; 29255404). Mutations of CIB2 have been associated with autosomal recessive nonsyndromic deafness 48 (DFNB48), as well as syndromic deafness in Usher syndrome, type 1J (USH1J) (PMID: 23331261). The observed molecular weight of CIB2 is 39 kDa because it can form a dimer (PMID: 30174586).