CIP2A Monoklonaler Antikörper
CIP2A Monoklonal Antikörper für WB, IF/ICC, Indirect ELISA
Wirt / Isotyp
Maus / IgG1
Getestete Reaktivität
human, Ratte
Anwendung
WB, IF/ICC, Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
2A3F3
Kat-Nr. : 67843-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
67843-1-PBS bindet in WB, IF/ICC, Indirect ELISA CIP2A und zeigt Reaktivität mit human, Ratten
Getestete Reaktivität | human, Ratte |
Wirt / Isotyp | Maus / IgG1 |
Klonalität | Monoklonal |
Typ | Antikörper |
Immunogen | CIP2A fusion protein Ag19598 |
Vollständiger Name | KIAA1524 |
Berechnetes Molekulargewicht | 905 aa, 102 kDa |
Beobachtetes Molekulargewicht | 102 kDa |
GenBank-Zugangsnummer | BC130564 |
Gene symbol | CIP2A |
Gene ID (NCBI) | 57650 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Protein-G-Reinigung |
Lagerungspuffer | PBS only |
Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
Cancerous inhibitor of protein phosphatase 2A (CIP2A) was originally identified as a cellular protein phosphatase 2A (PP2A) inhibitor, and has been shown to control oncogenic cellular signals by suppressing the tumor suppressor PP2A. CIP2A overexpression has been found in several human malignancies including breast cancer, hepatocellular carcinoma, gastric cancer, head and neck cancer, colon cancer, prostate cancer and non-small cell lung cancer. CIP2A is a 83~102 kDa cytoplasmic protein. ( PMID: 26824320, PMID: 25458953, PMID: 29720672)