CIR Polyklonaler Antikörper

CIR Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32928-1-PBS

Synonyme

CBF1-interacting corepressor, CIR1, Corepressor interacting with RBPJ 1, Recepin

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  WB analysis using 32928-1-AP (same clone as 32928-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32928-1-AP (CIR antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32928-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

32928-1-PBS bindet in WB, Indirect ELISA CIR und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: CIR fusion protein Ag38647
• Vollständiger Name: CBF1 interacting corepressor
• Berechnetes Molekulargewicht: 52kDa，450aa
• Beobachtetes Molekulargewicht: 23 kDa
• GenBank-Zugangsnummer: NM_004882.3
• Gene symbol: CIR
• Gene ID (NCBI): 9541
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CIR, a protein originally identified as a CBF1-interacting protein and reported to act as a transcriptional corepressor. CIR is a member of the family of SR-related proteins and that CIR plays a role in splicing regulation. In addition to a basic lysine and acidic serine-rich (BA) domain and a zinc knuckle-like motif, CIR has an arginine/serine dipeptide repeat (RS) domain in its C terminal region. The RS domain has been reported to be present in the superfamily of SR proteins, which are involved in splicing reactions (PMID: 15652350).