CISD1 Monoklonaler Antikörper
CISD1 Monoklonal Antikörper für WB, IHC, IF/ICC, Indirect ELISA
Wirt / Isotyp
Maus / IgG1
Getestete Reaktivität
Hausschwein, Huhn, human, Kaninchen, Maus, Ratte
Anwendung
WB, IHC, IF/ICC, Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
1D7E3
Kat-Nr. : 68030-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
68030-1-PBS bindet in WB, IHC, IF/ICC, Indirect ELISA CISD1 und zeigt Reaktivität mit Hausschwein, Huhn, human, Kaninchen, Maus, Ratten
Getestete Reaktivität | Hausschwein, Huhn, human, Kaninchen, Maus, Ratte |
Wirt / Isotyp | Maus / IgG1 |
Klonalität | Monoklonal |
Typ | Antikörper |
Immunogen | CISD1 fusion protein Ag8560 |
Vollständiger Name | CDGSH iron sulfur domain 1 |
Berechnetes Molekulargewicht | 108 aa, 12 kDa |
Beobachtetes Molekulargewicht | 14-17 kDa |
GenBank-Zugangsnummer | BC007043 |
Gene symbol | CISD1 |
Gene ID (NCBI) | 55847 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Protein-G-Reinigung |
Lagerungspuffer | PBS only |
Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
MitoNEET, also named CISD1, belongs to a previously uncharacterized ancient family of proteins for which the hallmark is the presence of a unique 39 amino acid CDGSH domain. It is a single-pass type III membrane protein, located in mitochondrion outer membrane and may play a role in regulating maximal capacity for electron transport and oxidative phosphorylation. MitoNEET is a recently identified drug target for a commonly prescribed diabetes drug, Pioglitazone. This antibody recognizing MitoNEET (calculated 12 kDa) as a 17 kDa protein may be due to its posttranslational modification or metal binding activity.