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CLCN7 Polyklonaler Antikörper

CLCN7 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 29230-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using CLCN7 Polyclonal antibody (29230-1-AP)

    WB analysis using 29230-1-AP (same clone as 29230-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 29230-1-AP (CLCN7 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29230-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

29230-1-PBS bindet in WB, Indirect ELISA CLCN7 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen CLCN7 fusion protein Ag29882
Vollständiger Name chloride channel 7
Berechnetes Molekulargewicht 805 aa, 89 kDa
Beobachtetes Molekulargewicht70 kDa
GenBank-ZugangsnummerBC012737
Gene symbol CLCN7
Gene ID (NCBI) 1186
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The intracellular CLC chloride channel family members ClC-3, ClC-4, and ClC-5 have been proposed as the primary endosomal chloride conductance providers. ClC-7 is expressed in late endosomes and lysosomes, but there is disagreement in the literature regarding its contribution to acidification. More recently, the cystic fibrosis (CF) transmembrane conductance regulator chloride channel (CFTR) was proposed as the specific counter-ion conductance necessary for lysosomal acidification in alveolar macrophages. (PMID: 20566682)