Claudin 7 Polyklonaler Antikörper

Claudin 7 Polyklonal Antikörper für IHC, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

IHC, IF, ELISA

Konjugation

Unkonjugiert

Publikationen

10

Kat-Nr. : 10118-1-AP

Synonyme

CEPTRL2, Claudin 7, CLDN 7, CLDN7, CPETRL2, Hs.84359

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Galerie der Validierungsdaten

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  IHC staining of human breast cancer using 10118-1-AP

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 10118-1-AP (Claudin 7 antibody) at dilution of 1:800 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IHC staining of human breast cancer using 10118-1-AP

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 10118-1-AP (Claudin 7 antibody) at dilution of 1:800 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

• 

  IHC staining of human breast cancer using 10118-1-AP

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 10118-1-AP (Claudin 7 antibody at dilution of 1:100 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

• 

  IHC staining of human breast cancer using 10118-1-AP

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 10118-1-AP (Claudin 7 antibody at dilution of 1:100 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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Geprüfte Anwendungen

• Erfolgreiche Detektion in IHC: humanes Mammakarzinomgewebe; Hinweis: Antigendemaskierung mit TE-Puffer pH 9,0 empfohlen. (*) Wahlweise kann die Antigendemaskierung auch mit Citratpuffer pH 6,0 erfolgen.

Empfohlene Verdünnung

• Immunhistochemie (IHC): IHC : 1:200-1:800

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• IHC: See 1 publications below
• IF: See 5 publications below

Produktinformation

10118-1-AP bindet in IHC, IF, ELISA Claudin 7 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• In Publikationen genannte Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Claudin 7 fusion protein Ag0159
• Vollständiger Name: claudin 7
• Berechnetes Molekulargewicht: 22.4 kDa
• Beobachtetes Molekulargewicht: 23 kDa
• GenBank-Zugangsnummer: BC001055
• Gene symbol: CLDN7
• Gene ID (NCBI): 1366
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Claudins are a family of proteins that are the most important components of tight junctions, where they establish the paracellular barrier that controls the flow of molecules in the intercellular space between the cells of an epithelium. They are small (20-27 kilodalton (kDa)) proteins with very similar structures. They have four transmembrane domains, with the N-terminus and the C-terminus in the cytoplasm.

Publikationen

Species	Application	Title
human		Cancers (Basel); Targeting PVT1 Exon 9 Re-Expresses Claudin 4 Protein and Inhibits Migration by Claudin-Low Triple Negative Breast Cancer Cells.; Authors - Fayola Levine
mouse	IF	iScience; Commercial dishes with gelatin-free microstructured inserts for elongated stem cell self-renewal and pluripotency; Authors - Qian Ban
mouse		Stem Cell Res Ther; Human menstrual blood-derived stem cell transplantation suppresses liver injury in DDC-induced chronic cholestasis.; Authors - Ya Yang
mouse	IF	FASEB J; Steroid receptor coactivator-2 drives epithelial reprogramming that enables murine embryo implantation; Authors - Vineet K Maurya
mouse		Front Pharmacol; Berberine Improves Irinotecan-Induced Intestinal Mucositis Without Impairing the Anti-colorectal Cancer Efficacy of Irinotecan by Inhibiting Bacterial β-glucuronidase.; Authors - Bei Yue
mouse	IF	Biol Reprod; Pre-implantation triclosan exposure alters uterine receptivity through affecting tight junction protein†.; Authors - Guangzhu Dong

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