CLEC10A/CD301 Rekombinanter Antikörper
CLEC10A/CD301 Rekombinant Antikörper für WB, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human, Maus
Anwendung
WB, Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
241857C3
Kat-Nr. : 84748-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
84748-1-PBS bindet in WB, Indirect ELISA CLEC10A/CD301 und zeigt Reaktivität mit human, Maus
Getestete Reaktivität | human, Maus |
Wirt / Isotyp | Kaninchen / IgG |
Klonalität | Rekombinant |
Typ | Antikörper |
Immunogen | Rekombinantes Protein |
Vollständiger Name | C-type lectin domain family 10, member A |
Berechnetes Molekulargewicht | 316 aa, 35 kDa |
Beobachtetes Molekulargewicht | 35 kDa |
GenBank-Zugangsnummer | BC039011 |
Gene symbol | CLEC10A |
Gene ID (NCBI) | 10462 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Protein A purfication |
Lagerungspuffer | PBS only |
Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
C-type lectin domain family 10 member A (CLEC10A), also known as CD301, macrophage galactose-type C-type lectin (MGL), DC-asialoglyco protein receptor (DC-ASGP-R) or human macrophage lectin (HML), is a type II transmembrane glycoprotein having a calcium-dependent carbohydrate recognition domain (PMID: 8598452; 11919201; 11698450). CLEC10A is expressed exclusively by myeloid professional antigen-presenting cells such as immature dendritic cells (DCs) and alternatively activated macrophages (PMID: 16998493). CLEC10A is a marker for human CD1c+ DCs (cDC2) (PMID: 29755453). It functions as an endocytic receptor for glycosylated antigens (PMID: 11919201).