CLEC10A/CD301 Rekombinanter Antikörper
CLEC10A/CD301 Rekombinant Antikörper für WB, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
Maus
Anwendung
WB, Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
242636A8
Kat-Nr. : 85911-5-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
85911-5-PBS bindet in WB, Indirect ELISA CLEC10A/CD301 und zeigt Reaktivität mit Maus
| Getestete Reaktivität | Maus |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Rekombinant |
| Typ | Antikörper |
| Immunogen | CLEC10A/CD301 fusion protein Eg2698 |
| Vollständiger Name | macrophage galactose N-acetyl-galactosamine specific lectin 1 |
| Berechnetes Molekulargewicht | 35 kDa |
| Beobachtetes Molekulargewicht | 40 kDa |
| GenBank-Zugangsnummer | NM_010796.3 |
| Gene symbol | Mgl1 |
| Gene ID (NCBI) | 17312 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Protein-A-Reinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
C-type lectin domain family 10 member A (CLEC10A), also known as CD301, macrophage galactose-type C-type lectin (MGL), DC-asialoglyco protein receptor (DC-ASGP-R) or human macrophage lectin (HML), is a type II transmembrane glycoprotein having a calcium-dependent carbohydrate recognition domain (PMID: 8598452; 11919201; 11698450). CLEC10A is expressed exclusively by myeloid professional antigen-presenting cells such as immature dendritic cells (DCs) and alternatively activated macrophages (PMID: 16998493). CLEC10A is a marker for human CD1c+ DCs (cDC2) (PMID: 29755453). It functions as an endocytic receptor for glycosylated antigens (PMID: 11919201).

