CLEC10A/CD301 Rekombinanter Antikörper

CLEC10A/CD301 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

242636F7

Kat-Nr. : 98437-1-RR

Synonyme

Clec10a, C-type lectin domain family 10 member A, Macrophage asialoglycoprotein-binding protein 1, Macrophage galactose/N-acetylgalactosamine-specific lectin, M-ASGP-BP-1

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  FC experiment of Transfected HEK-293T using 98437-1-RR

  1x10^6 HEK-293T cells or CLEC10A/CD301 transfected HEK-293T cells were surface stained with 0.25 ug Anti-Mouse CLEC10A/CD301 Rabbit RecAb (98437-1-RR, Clone:242636F7) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

• 

  FC experiment of Transfected HEK-293T using 98437-1-RR

  1x10^6 HEK-293T cells or CLEC10A/CD301 transfected HEK-293T cells were surface stained with 0.25 ug Anti-Mouse CLEC10A/CD301 Rabbit RecAb (98437-1-RR, Clone:242636F7) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: Transfected HEK-293T cells

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

98437-1-RR bindet in FC CLEC10A/CD301 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CLEC10A/CD301 fusion protein Eg2698
• Vollständiger Name: macrophage galactose N-acetyl-galactosamine specific lectin 1
• Berechnetes Molekulargewicht: 35 kDa
• GenBank-Zugangsnummer: NM_010796.3
• Gene symbol: Mgl1
• Gene ID (NCBI): 17312
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2 - 8°C. Stable for one year after shipment.

Hintergrundinformationen

C-type lectin domain family 10 member A (CLEC10A), also known as CD301, macrophage galactose-type C-type lectin (MGL), DC-asialoglyco protein receptor (DC-ASGP-R) or human macrophage lectin (HML), is a type II transmembrane glycoprotein having a calcium-dependent carbohydrate recognition domain (PMID: 8598452; 11919201; 11698450). CLEC10A is expressed exclusively by myeloid professional antigen-presenting cells such as immature dendritic cells (DCs) and alternatively activated macrophages (PMID: 16998493). CLEC10A is a marker for human CD1c+ DCs (cDC2) (PMID: 29755453). It functions as an endocytic receptor for glycosylated antigens (PMID: 11919201).