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CLEC5A Polyklonaler Antikörper

CLEC5A Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 18248-1-PBS

Synonyme

MDL-1, MDL1, MDL 1, C-type lectin superfamily member 5, C-type lectin domain family 5 member A

Filter:
  • Western Blot (WB) analysis of various lysates using CLEC5A Polyclonal antibody (18248-1-AP)

    WB analysis using 18248-1-AP (same clone as 18248-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 18248-1-AP (CLEC5A antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18248-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

18248-1-PBS bindet in WB, Indirect ELISA CLEC5A und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen CLEC5A fusion protein Ag13025
Vollständiger Name C-type lectin domain family 5, member A
Berechnetes Molekulargewicht 188 aa, 22 kDa
Beobachtetes Molekulargewicht36 kDa
GenBank-ZugangsnummerBC112099
Gene symbol CLEC5A
Gene ID (NCBI) 23601
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

C-type lectin domain family 5 member A (CLEC5A, also known as CLECSF5 and MDL1) is a spleen tyrosine kinase (Syk)-coupled receptor abundantly expressed by monocytes, macrophages and neutrophils (PMID: 10449773). It has a pivotal function in activating multiple aspects of innate immunity against bacterial invasion (PMID: 28824166). Both in vitro and in vivo evidence supported that CLEC5A was involved in glioblastoma pathogenesis via regulation of PI3K/Akt pathway (PMID: 30834619). It appeared as a protein band of ~36 kDa because of glycosylation, while its predicted molecular weight is 22 kDa (PMID: 25877931; 19074552).