CLEC5A Rekombinanter Antikörper

CLEC5A Rekombinant Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

251734A11

Kat-Nr. : 86633-2-RR

Synonyme

CLECSF5, C-type lectin domain family 5 member A, C-type lectin superfamily member 5, MDL 1, MDL1

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  WB analysis using 86633-2-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 86633-2-RR (CLEC5A antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours.

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  WB analysis using 86633-2-RR

  U-87 MG cells lysate was subjected to SDS PAGE followed by western blot with 86633-2-RR (CLEC5A antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: U-251-Zellen, K-562-Zellen, THP-1-Zellen, U-87 MG-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:1000-1:6000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

86633-2-RR bindet in WB, ELISA CLEC5A und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: DNA
• Vollständiger Name: C-type lectin domain family 5, member A
• Berechnetes Molekulargewicht: 188 aa, 22 kDa
• Beobachtetes Molekulargewicht: 22 kDa
• GenBank-Zugangsnummer: BC112099
• Gene symbol: CLEC5A
• Gene ID (NCBI): 23601
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

C-type lectin domain family 5 member A (CLEC5A, also known as CLECSF5 and MDL1) is a spleen tyrosine kinase (Syk)-coupled receptor abundantly expressed by monocytes, macrophages and neutrophils (PMID: 10449773). It has a pivotal function in activating multiple aspects of innate immunity against bacterial invasion (PMID: 28824166). Both in vitro and in vivo evidence supported that CLEC5A was involved in glioblastoma pathogenesis via regulation of PI3K/Akt pathway (PMID: 30834619).