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CLN5 Rekombinanter Antikörper

CLN5 Rekombinant Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242812H6

Kat-Nr. : 85378-1-PBS

Synonyme

242812H6, Bis(monoacylglycero)phosphate synthase CLN5, Bis(monoacylglycero)phosphate synthase CLN5, secreted form, BMP synthase CLN5, BMPS

Filter:
  • Western Blot (WB) analysis of various lysates using CLN5 Recombinant antibody (85378-1-RR)

    WB analysis using 85378-1-RR (same clone as 85378-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85378-1-RR (CLN5 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85378-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of A431 cells using CLN5 Recombinant antibody (85378-1-RR)

    IF Staining of A431 using 85378-1-RR (same clone as 85378-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed A431 cells using CLN5 antibody (85378-1-RR, Clone: 242812H6 ) at dilution of 1:500 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 85378-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

85378-1-PBS bindet in WB, IF/ICC, Indirect ELISA CLN5 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen CLN5 fusion protein Ag18175
Vollständiger Name ceroid-lipofuscinosis, neuronal 5
Berechnetes Molekulargewicht 407 aa, 46 kDa
Beobachtetes Molekulargewicht48 kDa
GenBank-ZugangsnummerBC153154
Gene symbol CLN5
Gene ID (NCBI) 1203
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The CLN5 (ceroid lipofuscinosis neuronal protein 5) protein is ubiquitously expressed in the majority of tissues studied and in the brain, CLN5 shows both neuronal and glial cell expression. CLN5 plays a role in maintaining an acidic environment in the lysosomes, a critical feature for a functional lysosome (PMID: 38236309). Moreover, CLN5-deficient neuronal progenitor cells showed reduced thioesterase activity, confirming the live cell function of CLN5 in setting S-depalmitoylation levels (PMID: 35427157).