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CLSTN3 Rekombinanter Antikörper

CLSTN3 Rekombinant Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Ratte

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

240865C10

Kat-Nr. : 83931-1-PBS

Synonyme

Alc-beta, alcbeta, Alcadein-beta, Alcadein beta, Alc beta

Filter:
  • Western Blot (WB) analysis of various lysates using CLSTN3 Recombinant antibody (83931-1-RR)

    WB analysis using 83931-1-RR (same clone as 83931-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 83931-1-RR (CLSTN3 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83931-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83931-1-RR

    Affinity and Kinetic Characterization of 83931-1-RR

    Biolayer interferometry (BLl) kinetic assays of 83931-1-RR against Human CLSTN3 were performed. The affinity constant is 1.51 nM.

Geprüfte Anwendungen

Produktinformation

83931-1-PBS bindet in WB, ELISA CLSTN3 und zeigt Reaktivität mit human, Ratten

Getestete Reaktivität human, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen CLSTN3 fusion protein Ag14897
Vollständiger Name calsyntenin 3
Berechnetes Molekulargewicht 968 aa, 107 kDa
GenBank-ZugangsnummerBC039075
Gene symbol CLSTN3
Gene ID (NCBI) 9746
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Calsyntenins, also called alcadeins, are cadherin superfamily proteins first identified as synaptic proteins (PMID: 11161476; 12498782). Calsyntenins are type I transmembrane proteins with extracellular domains containing two cadherin repeats and an LNS (laminin, neurexin, sex hormone-binding globulin) domain (PMID: 24613359). Calsyntenin-3 (CLSTN3, also known as alcadein-beta) is a synapse-organizing protein that promotes the development of synapses. It is a postsynaptic adhesion molecule that binds to presynaptic neurexins to mediate both excitatory and inhibitory synapse formation (PMID: 25352602; 24613359).