CLSTN3 Rekombinanter Antikörper

CLSTN3 Rekombinant Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Ratte

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

240865C10

Kat-Nr. : 83931-1-RR

Synonyme

Alc-beta, alcbeta, Alcadein-beta, Alcadein beta, Alc beta

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  WB analysis using 83931-1-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 83931-1-RR (CLSTN3 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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  Affinity and Kinetic Characterization of 83931-1-RR

  Biolayer interferometry (BLl) kinetic assays of 83931-1-RR against Human CLSTN3 were performed. The affinity constant is 1.51 nM.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: Rattenhirngewebe, Ratten-Cerebellum-Gewebe

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

83931-1-RR bindet in WB, ELISA CLSTN3 und zeigt Reaktivität mit human, Ratten

• Getestete Reaktivität: human, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CLSTN3 fusion protein Ag14897
• Vollständiger Name: calsyntenin 3
• Berechnetes Molekulargewicht: 968 aa, 107 kDa
• Beobachtetes Molekulargewicht: 130 kDa, 140 kDa
• GenBank-Zugangsnummer: BC039075
• Gene symbol: CLSTN3
• Gene ID (NCBI): 9746
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Calsyntenins, also called alcadeins, are cadherin superfamily proteins first identified as synaptic proteins (PMID: 11161476; 12498782). Calsyntenins are type I transmembrane proteins with extracellular domains containing two cadherin repeats and an LNS (laminin, neurexin, sex hormone-binding globulin) domain (PMID: 24613359). Calsyntenin-3 (CLSTN3, also known as alcadein-beta) is a synapse-organizing protein that promotes the development of synapses. It is a postsynaptic adhesion molecule that binds to presynaptic neurexins to mediate both excitatory and inhibitory synapse formation (PMID: 25352602; 24613359).