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CLUH Polyklonaler Antikörper

CLUH Polyklonal Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Affe, human, Maus

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 30986-1-PBS

Synonyme

KIAA0664, CLU1, FLJ23672, Protein KIAA0664

Filter:
  • Western Blot (WB) analysis of various lysates using CLUH Polyclonal antibody (30986-1-AP)

    WB analysis using 30986-1-AP (same clone as 30986-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30986-1-AP (CLUH antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30986-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using CLUH Polyclonal antibody (30986-1-AP)

    WB analysis using 30986-1-AP (same clone as 30986-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30986-1-AP (CLUH antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30986-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of COS-7 cells using CLUH Polyclonal antibody (30986-1-AP)

    IF Staining of COS-7 using 30986-1-AP (same clone as 30986-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed COS-7 cells using CLUH antibody (30986-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 30986-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

30986-1-PBS bindet in WB, IF/ICC, Indirect ELISA CLUH und zeigt Reaktivität mit Affe, human, Maus

Getestete Reaktivität Affe, human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen CLUH fusion protein Ag34275
Vollständiger Name KIAA0664
Beobachtetes Molekulargewicht147-150 kDa
GenBank-ZugangsnummerBC156940
Gene symbol CLUH
Gene ID (NCBI) 23277
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Clustered mitochondria homolog (CLUH) is a conserved RNA-binding protein, that binds transcripts encoding proteins involved in the respiratory chain, the tricarboxylic acid (TCA) cycle, and other mitochondrial metabolic pathways. Upon loss of CLUH, target mRNAs are subjected to faster decay, and their respective proteins are decreased in abundance. This leads to alterations in mitochondrial distribution (mitochondrial clustering as the gene name alludes to) mitochondrial cristae integrity, respiratory defects, loss of mtDNA, and decreased activity of TCA cycle enzymes. (PMID: 35559794)