CLUL1 Polyklonaler Antikörper
CLUL1 Polyklonal Antikörper für WB, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human
Anwendung
WB, Indirect ELISA
Konjugation
Unkonjugiert
Kat-Nr. : 27498-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
27498-1-PBS bindet in WB, Indirect ELISA CLUL1 und zeigt Reaktivität mit human
| Getestete Reaktivität | human |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Polyklonal |
| Typ | Antikörper |
| Immunogen | CLUL1 fusion protein Ag26570 |
| Vollständiger Name | clusterin-like 1 (retinal) |
| Berechnetes Molekulargewicht | 54 kDa |
| Beobachtetes Molekulargewicht | 70 kDa |
| GenBank-Zugangsnummer | BC025381 |
| Gene symbol | CLUL1 |
| Gene ID (NCBI) | 27098 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Antigen-Affinitätsreinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
Clusterin-like protein 1 (CLUL1) functions as a molecular chaperone, protecting stressed proteins, and is upregulated in various neurodegenerative conditions, suggesting a role in defense against neuronal damage (PMID: 17148042). It is specifically expressed in cone photoreceptor cells and is regulated by the cone-rod homeobox (CRX) (PMID: 14507903). Mutations of CLUL1 were investigated in the context of age-related macular degeneration (AMD), a leading cause of blindness in the elderly (PMID: 17148042).

