CLUL1 Polyklonaler Antikörper

CLUL1 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 27498-1-PBS

Synonyme

Retinal-specific clusterin-like protein, Clusterin-like protein 1, Clusterin like protein 1, clusterin like 1 (retinal)



Geprüfte Anwendungen

Produktinformation

27498-1-PBS bindet in WB, Indirect ELISA CLUL1 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen CLUL1 fusion protein Ag26570
Vollständiger Name clusterin-like 1 (retinal)
Berechnetes Molekulargewicht 54 kDa
Beobachtetes Molekulargewicht70 kDa
GenBank-ZugangsnummerBC025381
Gene symbol CLUL1
Gene ID (NCBI) 27098
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Clusterin-like protein 1 (CLUL1) functions as a molecular chaperone, protecting stressed proteins, and is upregulated in various neurodegenerative conditions, suggesting a role in defense against neuronal damage (PMID: 17148042). It is specifically expressed in cone photoreceptor cells and is regulated by the cone-rod homeobox (CRX) (PMID: 14507903). Mutations of CLUL1 were investigated in the context of age-related macular degeneration (AMD), a leading cause of blindness in the elderly (PMID: 17148042).