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CMPK2 Polyklonaler Antikörper

CMPK2 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 25877-1-PBS

Synonyme

EC:2.7.4.14, EC:2.7.4.6, Nucleoside-diphosphate kinase, TYKi, UMP CMPK2

Filter:
  • Western Blot (WB) analysis of various lysates using CMPK2 Polyclonal antibody (25877-1-AP)

    WB analysis using 25877-1-AP (same clone as 25877-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 25877-1-AP (CMPK2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25877-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human lung cancer tissue using CMPK2 Polyclonal antibody (25877-1-AP)

    IHC staining of human lung cancer using 25877-1-AP (same clone as 25877-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 25877-1-AP (CMPK2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 25877-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

25877-1-PBS bindet in WB, IHC, Indirect ELISA CMPK2 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen CMPK2 fusion protein Ag22885
Vollständiger Name cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
Berechnetes Molekulargewicht 449 aa, 49 kDa
Beobachtetes Molekulargewicht 55 kDa
GenBank-ZugangsnummerBC141802
Gene symbol CMPK2
Gene ID (NCBI) 129607
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CMPK2 belongs to the thymidylate kinase family. CMPK2 may participate in dUTP and dCTP synthesis in mitochondria. It is able to phosphorylate dUMP, dCMP, CMP, UMP and monophosphates of the pyrimidine nucleoside analogs ddC, dFdC, araC, BVDU and FdUrd with ATP as phosphate donor. Efficacy of CMPK2 is highest for dUMP followed by dCMP; CMP and UMP are poor substrates. CMPK2 may be involved in mtDNA depletion caused by long term treatment with ddC or other pyrimidine analogs.