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CNDP2 Polyklonaler Antikörper

CNDP2 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 30025-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using CNDP2 Polyclonal antibody (30025-1-AP)

    WB analysis using 30025-1-AP (same clone as 30025-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30025-1-AP (CNDP2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30025-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

30025-1-PBS bindet in WB, Indirect ELISA CNDP2 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen CNDP2 fusion protein Ag32312
Vollständiger Name CNDP dipeptidase 2 (metallopeptidase M20 family)
Berechnetes Molekulargewicht 53 kDa
Beobachtetes Molekulargewicht 44-53 kDa
GenBank-ZugangsnummerBC001375
Gene symbol CNDP2
Gene ID (NCBI) 55748
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Carnosine dipeptidase II (CNDP2) catalyzes the peptide bond hydrolysis in dipeptides, displaying a non-redundant activity toward threonyl dipeptides. It has high dipeptidase activity toward cysteinyl glycine, an intermediate metabolite in glutathione metabolism (PubMed:19346245, PubMed:12473676). Metabolizes N-lactoyl-amino acids, both through hydrolysis to form lactic acid and amino acids, as well as through their formation by reverse proteolysis (PubMed:25964343). CNDP2 has 2 isoforms with a molecular weight of 53 and 44 kDa. The isoform 1 is ubiquitously expressed with higher levels in the kidney and liver (at protein level) and expressed in peripheral blood leukocytes (PubMed:12473676). It is also expressed in gastric mucosa and down-regulated in gastric cancer mucosal tissues (at the protein level) (PubMed:24395568). Isoform 2 is broadly expressed in fetal tissues and expressed in the adult liver and placenta. (PMID: 17121880).