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CNGA4 Polyklonaler Antikörper

CNGA4 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 22201-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using CNGA4 Polyclonal antibody (22201-1-AP)

    WB analysis using 22201-1-AP (same clone as 22201-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 22201-1-AP (CNGA4 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22201-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

22201-1-PBS bindet in WB, Indirect ELISA CNGA4 und zeigt Reaktivität mit Maus, Ratten

Getestete Reaktivität Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen CNGA4 fusion protein Ag17481
Vollständiger Name cyclic nucleotide gated channel alpha 4
Berechnetes Molekulargewicht 575 aa, 66 kDa
Beobachtetes Molekulargewicht47-50 kDa, 65-70 kDa
GenBank-ZugangsnummerBC106936
Gene symbol CNGA4
Gene ID (NCBI) 1262
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CNGA4 (cyclic nucleotide gated channel subunit alpha 4), also known as CNG4. It is expected to be located in cell membrane. Cyclic nucleotide-gated (CNG) channels are crucial for visual and olfactory transductions (PMID: 12432397). Native CNG channels are heterotetramers composed of homologous A and B subunits. Olfactory CNG channels are composed of three types of subunits, CNGA2, CNGA4, and CNGB1b (PMID: 15134638). CNGA4 is a modulatory subunit which contributes to the high cAMP sensitivity of the native olfactory channel. By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation of native olfactory neurons to odorants (PMID: 11739959; 11739960). The molecular weight of CNGA4 is 65 kDa, and it can recognize the 48 kDa isoform.