CNNM3 Polyklonaler Antikörper

CNNM3 Polyklonal Antikörper für WB, IHC, IF/ICC, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, IF/ICC, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 13976-1-PBS

Synonyme

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  WB analysis using 13976-1-AP (same clone as 13976-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 13976-1-AP (CNNM3 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13976-1-PBS in a different storage buffer formulation.

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  IP experiment of K-562 using 13976-1-AP (same clone as 13976-1-PBS)

  IP result of anti-CNNM3 (IP:13976-1-AP, 4ug; Detection:13976-1-AP 1:500) with K-562 cells lysate 3600ug. This data was developed using the same antibody clone with 13976-1-PBS in a different storage buffer formulation.

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  IHC staining of human spleen using 13976-1-AP (same clone as 13976-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human spleen using 13976-1-AP (CNNM3 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 13976-1-PBS in a different storage buffer formulation.

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  IHC staining of human spleen using 13976-1-AP (same clone as 13976-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human spleen using 13976-1-AP (CNNM3 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 13976-1-PBS in a different storage buffer formulation.

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  IF Staining of A431 using 13976-1-AP (same clone as 13976-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed A431 cells using CNNM3 antibody (13976-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 13976-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

13976-1-PBS bindet in WB, IHC, IF/ICC, IP, Indirect ELISA CNNM3 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: CNNM3 fusion protein Ag5012
• Vollständiger Name: cyclin M3
• Berechnetes Molekulargewicht: 76 kDa
• Beobachtetes Molekulargewicht: 85 kDa
• GenBank-Zugangsnummer: BC037272
• Gene symbol: CNNM3
• Gene ID (NCBI): 26505
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Human Cyclin M 3 (CNNM3) has five transmembrane domains located at the N-terminal region and a C terminus containing a CBS pair domain and a cyclin box, both of which are part of the ACD region. CNNM3 magnesium transporter raises the intracellular magnesium content of cancer cells contributing to increased tumor growth and the acquisition of oncogenic properties (PMID: 24632616).