CNNM4 Rekombinanter Antikörper

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• KD/KO Validated

CNNM4 Rekombinant Antikörper für WB, Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

240873E9

Kat-Nr. : 83824-4-PBS

Synonyme

240873E9, ACDP4, Ancient conserved domain-containing protein 4, cyclin M4, Cyclin-M4

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  WB analysis of HEK-293 using 83824-4-RR (same clone as 83824-4-PBS)

  WB result of CNNM4 antibody (83824-4-RR; 1:2000; incubated at room temperature for 1.5 hours) with sh-Control and sh-CNNM4 transfected HEK-293 cells. This data was developed using the same antibody clone with 83824-4-PBS in a different storage buffer formulation.

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  WB analysis using 83824-4-RR (same clone as 83824-4-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 83824-4-RR (CNNM4 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83824-4-PBS in a different storage buffer formulation.

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  Cytometric bead array standard curve of MP00802-3

  Cytometric bead array standard curve of MP00802-3, CNNM4 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 83824-4-PBS. Detection antibody: 83824-2-PBS. Standard: Ag5121. Range: 0.313-40 ng/mL.

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  Affinity and Kinetic Characterization of 83824-4-RR

  Biolayer interferometry (BLl) kinetic assays of 83824-4-RR against Human CNNM4 were performed. The affinity constant is below 1 pM.

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Geprüfte Anwendungen

Produktinformation

83824-4-PBS bindet in WB, Cytometric bead array, Indirect ELISA CNNM4 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CNNM4 fusion protein Ag5121
• Vollständiger Name: cyclin M4
• Berechnetes Molekulargewicht: 87 kDa
• Beobachtetes Molekulargewicht: 90-100 kDa
• GenBank-Zugangsnummer: BC063295
• Gene symbol: CNNM4
• Gene ID (NCBI): 26504
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Ancient conserved domain-containing protein 4/cyclin M4 (CNNM4), a membrane protein that stimulates Mg2+ efflux, binds phosphatase of regenerating liver (PRL), which is frequently overexpressed in malignant human cancers (PMID: 25347473). CNNM4 is predominant in the brain, bone marrow, immune system, and especially abundant in the intestinal tract. CNNM4 localizes at the basolateral membrane of the intestinal epithelia and mediates transcellular Mg2+ transport (PMID: 27006114).