Cannabinoid receptor 1 Rekombinanter Antikörper

Cannabinoid receptor 1 Rekombinant Antikörper für WB, Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250285B1

Kat-Nr. : 82787-3-PBS

Synonyme

CNR1, CANN6, cannabinoid receptor 1 (brain), CB R, CB1

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  WB analysis of fetal human brain using 82787-3-RR (same clone as 82787-3-PBS)

  fetal human brain tissue were subjected to SDS PAGE followed by western blot with 82787-3-RR (CNR1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82787-3-PBS in a different storage buffer formulation.

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  WB analysis using 82787-3-RR (same clone as 82787-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 82787-3-RR (CNR1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82787-3-PBS in a different storage buffer formulation.

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  Cytometric bead array standard curve of MP02192-2

  Cytometric bead array standard curve of MP02192-2, Cannabinoid receptor 1 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 82787-5-PBS. Detection antibody: 82787-3-PBS. Standard: Ag12625. Range: 1.25-20 ng/mL.

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  Affinity and Kinetic Characterization of 82787-3-PBS

  Biolayer interferometry (BLl) kinetic assay of 82787-3-PBS against Human Cannabinoid receptor 1 was performed. The affinity constant is 3.81 nM.

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  Affinity and Kinetic Characterization of 82787-3-RR

  Biolayer interferometry (BLl) kinetic assays of 82787-3-RR against Human Cannabinoid receptor 1 were performed. The affinity constant is 6.29 nM.

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Geprüfte Anwendungen

Produktinformation

82787-3-PBS bindet in WB, Cytometric bead array, Indirect ELISA Cannabinoid receptor 1 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Cannabinoid receptor 1 fusion protein Ag12625
• Vollständiger Name: cannabinoid receptor 1 (brain)
• Berechnetes Molekulargewicht: 472 aa, 53 kDa
• Beobachtetes Molekulargewicht: 60 kDa
• GenBank-Zugangsnummer: BC074812
• Gene symbol: Cannabinoid receptor 1
• Gene ID (NCBI): 1268
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Cannabinoid receptor 1 (CNR1, or CB1) and CNR2 (CB2) are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family. The CB1 receptor is expressed mainly in the brain. The CB2 receptor is expressed mainly in the immune system and in hematopoietic cells. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana.