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CNTN1 Monoklonaler Antikörper

CNTN1 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

Hausschwein, human, Kaninchen

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1C1D4

Kat-Nr. : 68252-1-PBS

Synonyme

CNTN1, contactin 1, F3, Glycoprotein gp135, GP135, Neural cell surface protein F3

Filter:
  • Western Blot (WB) analysis of various lysates using CNTN1 Monoclonal antibody (68252-1-Ig)

    WB analysis using 68252-1-Ig (same clone as 68252-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68252-1-Ig (CNTN1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68252-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using CNTN1 Monoclonal antibody (68252-1-Ig)

    WB analysis using 68252-1-Ig (same clone as 68252-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68252-1-Ig (CNTN1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68252-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

68252-1-PBS bindet in WB, Indirect ELISA CNTN1 und zeigt Reaktivität mit Hausschwein, human, Kaninchen

Getestete Reaktivität Hausschwein, human, Kaninchen
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen CNTN1 fusion protein Ag5030
Vollständiger Name contactin 1
Berechnetes Molekulargewicht 1018 aa, 113 kDa
Beobachtetes Molekulargewicht130-135 kDa
GenBank-ZugangsnummerBC036569
Gene symbol CNTN1
Gene ID (NCBI) 1272
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Contactin-1 (CNTN1), also known as Glycoprotein gp135 or Neural cell surface protein F3, is a neuronal cell adhesion molecule of the immunoglobulin superfamily (PMID: 3049624). It consists of six Ig domains, four fibronectin-like motifs, and a glycosylphosphatidylinositol (GPI)-moiety. Expressed by the central and peripheral neurons, CNTN1 contributes to the formation and function of neuronal connections. It plays a role in axon extension and formation of septate-like junctions between axons and myelinating glial cells (PMID: 23724143). In addition, acting as a ligand for Notch, CNTN1 initiates a NOTCH/DTX1 signaling pathway that promotes oligodendrocyte maturation and myelination (PMID: 14567914).