COG4 Polyklonaler Antikörper

COG4 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31539-1-PBS

Synonyme

COD1, COG complex subunit 4

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  WB analysis using 31539-1-AP (same clone as 31539-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31539-1-AP (COG4 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31539-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 31539-1-AP (same clone as 31539-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31539-1-AP (COG4 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31539-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse testis using 31539-1-AP (same clone as 31539-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 31539-1-AP (COG4 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31539-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

31539-1-PBS bindet in WB, IHC, Indirect ELISA COG4 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: COG4 fusion protein Ag35295
• Vollständiger Name: component of oligomeric golgi complex 4
• Berechnetes Molekulargewicht: 89kDa，785aa
• Beobachtetes Molekulargewicht: 89 kDa
• GenBank-Zugangsnummer: NM_001365426.1
• Gene symbol: COG4
• Gene ID (NCBI): 25839
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

COG complex subunit 4 is present in high molecular weight complexes that govern membrane movement between the Golgi and ER. Cog4 dependent trafficking and secretion of ECM components are required for protrusion and extension of the epithelial projections of the inner ear (PMID: 30287385). Loss-of-function COG4-mutant cells have impaired glycosylation and reduced COG4 protein levels (PMID: 30290151).