COL4A6 Polyklonaler Antikörper

COL4A6 Polyklonal Antikörper für ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus und mehr (1)

Anwendung

WB, IHC, IF, ELISA

Konjugation

Unkonjugiert

Publikationen(8)

Kat-Nr. : 10807-1-AP

Synonyme

Collagen alpha 6(IV) chain, Collagen alpha-6(IV) chain, Collagen Type IV

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  WB analysis of SGC-7901 using 10807-1-AP

  SGC-7901 cells were subjected to SDS PAGE followed by western blot with 10807-1-AP (Collagen Type IV antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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  WB analysis of A431 using 10807-1-AP

  A431 cells were subjected to SDS PAGE followed by western blot with 10807-1-AP (Collagen Type IV antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

Veröffentlichte Anwendungen

• WB: See 4 publications below
• IHC: See 2 publications below
• IF: See 2 publications below

Produktinformation

10807-1-AP bindet in WB, IHC, IF, ELISA COL4A6 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• In Publikationen genannte Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: COL4A6 fusion protein Ag1118
• Vollständiger Name: collagen, type IV, alpha 6
• Berechnetes Molekulargewicht: 1691 aa, 164 kDa
• GenBank-Zugangsnummer: BC005305
• Gene symbol: COL4A6
• Gene ID (NCBI): 1288
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Collagen alpha-6(IV) chain, known as COL4A6, is a member of the collagen family, the major structural component of basement membranes. There are six type IV collagen isoforms, alpha 1(IV)-alpha 6(IV), each of which can form a triple helix structure with 2 other chains to generate type IV collagen network. COL4A6 forms a triple helical structure with two other alpha-5-chains, which is stabilized by the presence of glycine as every third residue (PMID: 27377778). COL4A6 is located on the X chromosome in a head-to-head manner with COL4A5 closely (PMID: 23714752). COL4A6 is transcribed from two alternative promoters in a tissue-specific fashion. This antibody detected the cleaved fragment of COL4A6 at ~50 kDa (PMID: 7657706)..

Publikationen

Species	Application	Title
human	WB	Oncogene; Hepatitis B virus X protein promotes the development of liver fibrosis and hepatoma through downregulation of miR-30e targeting P4HA2 mRNA.; Authors - G X Feng
human	IF	Polymers (Basel); The Development of a 3D PET Fibrous Scaffold Modified with an Umbilical Cord dECM for Liver Tissue Engineering; Authors - Yang Li
rat	WB	Toxicol Appl Pharmacol; High doses of baicalin induces kidney injury and fibrosis through regulating TGF-β/Smad signaling pathway.; Authors - Yi Cai
human	IHC	J Tissue Eng Regen Med; Topographical and Chemical Inductive Cues Synergistically Enhance the Schwann Cell Differentiation of Aligned Dental Pulp Stem Cell Sheets; Authors - Michelle D Drewry
human	IHC	J Immunol Res; Partial Reconstruction of Uterus Cervix in Rat by Decellularized Human Uterine Cervical Scaffold Combined with Adipose-Derived Stem Cells (ADSCs); Authors - Yuqi Li
mouse	IF	Oral Dis; Artemisinin suppressed tumour growth and induced vascular normalisation in oral squamous cell carcinoma via inhibition of MIF; Authors - Xiang-Hua Yu