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COL6A3 Polyklonaler Antikörper

COL6A3 Polyklonal Antikörper für IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 19798-1-PBS

Synonyme

Collagen alpha 3(VI) chain, Collagen alpha-3(VI) chain, Collagen Type VI

Filter:
  • Immunohistochemistry (IHC) staining of human cervical cancer tissue using COL6A3 Polyclonal antibody (19798-1-AP)

    IHC staining of human cervical cancer using 19798-1-AP (same clone as 19798-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 19798-1-AP (Collagen Type VI antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19798-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human lung cancer tissue using COL6A3 Polyclonal antibody (19798-1-AP)

    IHC staining of human lung cancer using 19798-1-AP (same clone as 19798-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 19798-1-AP (Collagen Type VI antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19798-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human urothelial carcinoma tissue using COL6A3 Polyclonal antibody (19798-1-AP)

    IHC staining of human urothelial carcinoma using 19798-1-AP (same clone as 19798-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human urothelial carcinoma tissue slide using 19798-1-AP (Collagen Type VI antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19798-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

19798-1-PBS bindet in IHC, Indirect ELISA COL6A3 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Peptid
Vollständiger Name collagen, type VI, alpha 3
Berechnetes Molekulargewicht 344 kDa
Beobachtetes Molekulargewicht300 kDa
GenBank-ZugangsnummerNM_004369
Gene symbol COL6A3
Gene ID (NCBI) 1293
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

COL6A3 belongs to the type VI collagen family. Collagen VI acts as a cell-binding protein. It is expected to be expressed in smooth muscle. And the calculated molecular weight of COL6A3 is 343 kDa. The protein has similar expression in obese and T2DM (2 patients, and it regulates the chemotaxis and inflammation of macrophages in adipose tissue. Its expression is also related to weight gain. The expression of this protein in adipocytes is related to insulin resistance, which is believed to depend on PPAR (peroxisome proliferator-activated receptor) α-mediated adipocyte development (PMID: 25337653). Defects in COL6A3 are a cause of Bethlem myopathy (BM). Defects in COL6A3 are a cause of Ullrich congenital muscular dystrophy (UCMD) which also known as Ullrich scleroatonic muscular dystrophy. This antibody is specific to COL6A3.