COL6A6 Polyklonaler Antikörper

COL6A6 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 22302-1-PBS

Synonyme

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  WB analysis using 22302-1-AP (same clone as 22302-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 22302-1-AP (COL6A6 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22302-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse lung using 22302-1-AP (same clone as 22302-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse lung tissue slide using 22302-1-AP (COL6A6 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22302-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse heart using 22302-1-AP (same clone as 22302-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 22302-1-AP (COL6A6 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22302-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

22302-1-PBS bindet in WB, IHC, Indirect ELISA COL6A6 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: collagen type VI alpha 6
• Berechnetes Molekulargewicht: 247 kDa
• Beobachtetes Molekulargewicht: 167 kDa, 250 kDa
• GenBank-Zugangsnummer: NM_001102608
• Gene symbol: COL6A6
• Gene ID (NCBI): 131873
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Collagen type VI alpha 6 chain (COL6A6) belongs to the collagen VI (COL6) family which acts as a vital role in the extracellular matrix. COL6A6 encodes a 2,262-amino acid protein that contains multiple von Willebrand factor domains and forms a component of the basal lamina of epithelial cells (PMID: 33747955). COL6A6 is a novel tumor suppressor gene in NSCLC and can serve as a potentially valuable prognostic biomarker and therapeutic target for NSCLC (PMID: 35116307).