COPS8/COP9 Polyklonaler Antikörper

COPS8/COP9 Polyklonal Antikörper für WB, IHC, IP, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, IP, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 10089-2-PBS

Synonyme

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  WB analysis using 10089-2-AP (same clone as 10089-2-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 10089-2-AP (COPS8/COP9 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10089-2-PBS in a different storage buffer formulation.

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  WB analysis of HepG2 using 10089-2-PBS

  HepG2 cells were subjected to SDS PAGE followed by western blot with 10089-2-AP (COPS8/COP9 antibody) at dilution of 1:1200 incubated at room temperature for 1.5 hours.

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  IP experiment of mouse brain using 10089-2-AP (same clone as 10089-2-PBS)

  IP result of anti-COPS8/COP9 (IP:10089-2-AP, 4ug; Detection:10089-2-AP 1:500) with mouse brain tissue lysate 3200 ug. This data was developed using the same antibody clone with 10089-2-PBS in a different storage buffer formulation.

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  IHC staining of human colon cancer using 10089-2-AP (same clone as 10089-2-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 10089-2-AP (COPS8/COP9 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10089-2-PBS in a different storage buffer formulation.

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  IHC staining of human colon cancer using 10089-2-AP (same clone as 10089-2-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 10089-2-AP (COPS8/COP9 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10089-2-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 10089-2-AP (same clone as 10089-2-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 10089-2-AP (COPS8/COP9 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10089-2-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 10089-2-AP (same clone as 10089-2-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 10089-2-AP (COPS8/COP9 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10089-2-PBS in a different storage buffer formulation.

• 

  IHC staining of human gliomas using 10089-2-AP (same clone as 10089-2-PBS)

  Immunohistochemical analysis of paraffin-embedded human gliomas tissue slide using 10089-2-AP (COPS8/COP9 antibody at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 10089-2-PBS in a different storage buffer formulation.

• 

  IHC staining of human gliomas using 10089-2-AP (same clone as 10089-2-PBS)

  Immunohistochemical analysis of paraffin-embedded human gliomas tissue slide using 10089-2-AP (COPS8/COP9 antibody at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 10089-2-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

10089-2-PBS bindet in WB, IHC, IP, ELISA COPS8/COP9 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: COPS8/COP9 fusion protein Ag0143
• Vollständiger Name: COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)
• Berechnetes Molekulargewicht: 23 kDa
• Beobachtetes Molekulargewicht: 23 kDa
• GenBank-Zugangsnummer: BC003090
• Gene symbol: COPS8
• Gene ID (NCBI): 10920
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

COPS8 is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases.

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